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Aktualności z zakresu medycyny ogólnej
- 05.03.2010 FDA Approves Changing Name of Kapidex to Dexilant
In late April, Takeda Pharmaceuticals will begin marketing its proton pump inhibitor Kapidex (dexlansoprazole) under the new name Dexilant, owing to dispensing errors that have occurred from mix-ups with the prostate cancer drug Casodex (bicalutamide) and the analgesic Kadian (morphine). + zobacz więcej - 05.03.2010 Talking Points: CDC Releases County-Level Atlas of Heart Disease Hospitalizations
The CDC recently released the 2010 Atlas of Heart Disease Hospitalizations Among Medicare Beneficiaries, its first atlas showing hospitalization rates for heart disease at the county level.
Hospitalization rates for 2000 to 2006 were highest among blacks and in counties in the Appalachian Mountains, the Mississippi Delta, Texas, and Oklahoma. Nearly two thirds of counties did not have a cardiologist, excluding those at Veterans Affairs hospitals. + zobacz więcej - 04.03.2010 Glycated Hemoglobin Better Than Fasting Glucose for Predicting Cardiovascular Risk
Glycated hemoglobin levels, especially above 6.0%, are better than fasting glucose for predicting long-term cardiovascular risk, the New England Journal of Medicine reports.
Researchers measured glycated hemoglobin and fasting glucose in some 11,000 adults without diabetes or cardiovascular disease and followed them for a median of 14 years. Compared with hemoglobin levels of 5.0% to 5.5%, higher values — especially above 6% — were associated with significantly increased risks for diabetes, coronary heart disease, and stroke. Associations between hemoglobin and all-cause mortality were also significant, but formed a J-shaped curve, with the lowest and highest levels being predictive of death. + zobacz więcej - 03.03.2010 Asthma Step-Up Therapy: No Single Regimen Is Best for All Children
No single treatment regimen is best for all children requiring asthma step-up therapy, according to a randomized crossover study in the New England Journal of Medicine. + zobacz więcej - 03.03.2010 Aspirin Fails to Prevent Cardiovascular Events in Patients with a Low Ankle-Brachial Index
Giving aspirin to patients at increased risk for cardiovascular disease (on the basis of low ankle-brachial scores) apparently does not lower their risk, JAMA reports.
Researchers randomized some 3400 patients without clinically evident cardiovascular disease, but with ankle-brachial indexes of 0.95 or less, to either aspirin (100 mg per day) or placebo. Median age at entry was 62. + zobacz więcej - 03.03.2010 FDA Approves First Generic Version of Flomax
The first generic version of Flomax 0.4 mg (tamsulosin hydrochloride) has been approved to treat benign prostatic hyperplasia, the FDA announced on Tuesday. + zobacz więcej - 03.03.2010 Anemia Therapies in Dialysis Patients with Higher Hematocrit May Be 'Problematic'
Increased use of erythropoiesis-stimulating agents (ESAs) and iron treatments is associated with higher mortality rates in patients with end-stage renal disease who have relatively high hematocrit levels, according to an observational study in JAMA.
Researchers used Medicare data on end-stage renal disease to compare anemia management practices in some 270,000 patients starting hemodialysis. Centers that used larger doses of ESAs in patients with hematocrits under 30% had lower 1-year mortality rates, but when larger doses were used in patients with hematocrits of 33% or above, higher mortality rates were observed. A similar pattern was observed in the use of supplemental intravenous iron. + zobacz więcej - 02.03.2010 Adding Electrocardiography to Athletic Screening Appears Cost-Effective but Increases False-Positives
Adding 12-lead electrocardiography (ECG) to preparticipation athletic exams may be cost-effective, according to one study, while another finds that doing so increases false-positive findings. Both studies appear in the Annals of Internal Medicine.
Using published screening data, researchers found that adding ECG to a cardiovascular-focused history and physical exam saves roughly 2 life-years per 1000 athletes screened. This translates to a cost-effectiveness ratio of roughly $40,000 per life-year saved. + zobacz więcej - 01.03.2010 Carotid Stenting vs. Endarterectomy in High-Risk Patients
A North American study showing that carotid stenting may be as effective as endarterectomy in high-risk patients received a lot of press attention over the weekend. The findings were presented Friday at the International Stroke Conference in San Antonio.
In the industry-supported CREST study, some 2500 patients with symptomatic or asymptomatic partial carotid blockages (most with blockages over 70%) were randomized to undergo stenting or endarterectomy. + zobacz więcej - 01.03.2010 OneTouch SureStep Glucose Test Strips Recalled
LifeScan is recalling eight lots of its OneTouch SureStep glucose test strips because they may yield falsely low results when a patient's glucose level is above 400 mg/dL.
The company's press release includes the affected lot numbers. + zobacz więcej
