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- 30.07.2010 Calcium Supplements Reportedly Raise Risk for Myocardial Infarction
Patients on calcium supplements show a modest increase in risk for myocardial infarction, according to a BMJ meta-analysis.
Investigators gathered data on some 12,000 participants in randomized controlled trials using calcium supplements without vitamin D. Subjects on calcium showed a roughly 30% increase in risk for MI and nonsignificant increases for stroke, death, and the composite outcome of MI, stroke, or sudden death. + zobacz więcej - 30.07.2010 ACIP Publishes Recommendations for 2010–11 Influenza Vaccination
The CDC's Advisory Committee on Immunization Practices has published its recommendations on influenza vaccination for the 2010–11 season in MMWR.
Among the major changes from 2009:
Routine vaccination is now advised for all people aged 6 months and older. + zobacz więcej - 30.07.2010 Naltrexone-Bupropion Plus Lifestyle Changes Better Than Lifestyle Changes Alone for Weight Loss
Adding a naltrexone-bupropion pill to lifestyle changes leads to greater weight loss than lifestyle changes alone, according to a manufacturer-conducted, phase III study in the Lancet.
Researchers randomized some 1700 overweight or obese adults to daily treatment with either sustained-release naltrexone (16 or 32 mg) plus bupropion (360 mg), or placebo. All participants were also instructed to consume fewer calories and exercise more. + zobacz więcej - 29.07.2010 Bystander CPR Studies Seem to Confirm Value of Compression-Only Approach
Having bystanders initiate compression-only CPR after cardiac arrest is at least as effective as using compression plus rescue breathing, according to two studies in the New England Journal of Medicine.
Both studies used emergency telephone dispatchers to instruct bystanders to use either compression-only or standard CPR until emergency medical services personnel arrived. The dispatchers' recommended approach was governed by randomization. Patients with arrest due to trauma, asphyxiation, or drowning were excluded from both studies. + zobacz więcej - 29.07.2010 FDA Approves Glycopyrrolate for Chronic Drooling in Kids
The FDA has approved a liquid formulation of glycopyrrolate (Cuvposa) for chronic severe drooling caused by neurologic disorders in children aged 3 to 16 years. The drug was previously approved to treat peptic ulcers and reduce saliva production in patients undergoing anesthesia. + zobacz więcej - 27.07.2010 Only Certain Newer Antiepileptic Drugs Associated with Increased Risk for Suicidal Behavior
Current use of newer antiepileptic drugs (AEDs) that pose high risk for depression is associated with increased risk for suicidal behavior, according to an industry-funded study in Neurology. (In 2008, the FDA warned that all AEDs raise suicidality risk.)
Using a U.K. general practice database, researchers matched some 450 patients with epilepsy who had displayed self-harm or suicidal behavior with some 9000 epileptic patients without such behavior. All had used at least one AED during 5.5 years' follow-up. + zobacz więcej - 27.07.2010 Some Antiretrovirals Increase Risk for Myocardial Infarction
Some antiretroviral agents, but not all, increase the risk for myocardial infarction, according to an Archives of Internal Medicine study.
Researchers set out to settle an ongoing concern about abacavir, and then widened their purview. Using a French national database of HIV-infected patients, they identified almost 300 who had a definite or suspected initial MI while on treatment. The researchers then age- and sex-matched the cases with HIV-infected controls who did not have an MI. + zobacz więcej - 26.07.2010 Medical Marijuana Rules to Be Eased for Veterans
Patients may ask about a front-page story in Saturday's New York Times describing a new policy from the Department of Veterans Affairs: Veterans using medicinal marijuana in states where it's legal can no longer be denied access to pain medications because of their marijuana use.
Previously, pain treatments could be denied if patients were using any drug considered illegal by federal law, including marijuana. This led some veterans on medicinal marijuana to abandon the VA system altogether, a spokesperson for a veterans interest group told the Times. + zobacz więcej - 26.07.2010 FDA Approves First Generic Lovenox
The FDA on Friday approved the first generic version of the anticoagulant Lovenox (enoxaparin sodium injection).
Like the brand-name version, the generic's label includes a boxed warning about the risks for spinal or epidural hematoma in patients who receive the drug while undergoing neuraxial anesthesia or spinal puncture. + zobacz więcej - 23.07.2010 New CDC Guidelines for Use of Anthrax Vaccine
The CDC's Advisory Committee on Immunization Practices has updated its guidelines for use of the anthrax vaccine. They're available online in MMWR. + zobacz więcej
